12:00 PM: Kentucky @ (6) Ole Miss (ABC)
Announcers: Sean McDonough, Greg McElroy
The Wildcats visit the No. 6 Rebels. Entering Week 5, Ole Miss has averaged 55 points per game on offense and 5.5 ppg on defense, both tops in the nation. Jaxson Dart (MISS) led FBS with 1,554 passing yards. Ole Miss beat Kentucky 22-19 in 2022.
12:00 PM: Minnesota @ (12) Michigan (Fox)
Announcers: Gus Johnson, Joel Klatt
The No. 12 Wolverines host the Golden Gophers. In Week 4, Michigan switched to Alex Orji at quarterback, but the ground game starred in a win over then-No. 11 USC. Kalel Mullings (MICH) hit 150 rushing yards and two TDs for the second straight match.
12:00 PM: (20) Oklahoma State @ (23) Kansas State (ESPN)
Announcers: Bob Wischusen, Louis Riddick
No. 20 Oklahoma State plays No. 23 Kansas State. Both schools fell to 3-1, 0-1 with losses in their Big 12 openers. Last year, the Cowboys won for a fourth time in five meetings. However, the Wildcats walked all over the Cowboys 48-0 at home in 2022.
12:00 PM: Navy @ UAB (ESPN2)
Announcers: Roy Philpott, Sam Acho
The unbeaten Midshipmen roll into Birmingham, Ala., for a matchup with the Blazers. Dual-threat quarterback Blake Horvath has rushed for seven TDs and thrown for five more in helping Navy put up 143 points through its first three contests.
12:00 PM: (22) BYU @ Baylor (FS1)
Announcers: Alex Faust, Robert Smith
The No. 22 Cougars hit the road for a matchup with the Bears. BYU thumped then-No. 13 Kansas State 38-9 on Sept. 21 to crack the AP Top 25 for the first time in two years. Baylor fell to 2-2 with a loss in an overtime thriller at Colorado.
12:00 PM: South Florida @ Tulane (ESPNU)
Announcers: Matt Schumacker, Dustin Fox
A pair of 2-2 sides open their American Athletic Conference campaigns as the Green Wave host the Bulls. Tulane totaled 131 points in winning the last three meetings. Kelley Joiner (USF) averages seven yards per carry and has scored four TDs in 2024.
12:00 PM: Northern Illinois @ N.C. State (CW)
Announcers: Thom Brennaman, Max Browne
The Huskies hunt with the Wolfpack. Northern Illinois was dropped from the AP Top 25, its first appearance in 11 years, following a 23-20 setback in overtime versus Buffalo. NC State has won six straight at home, and is 2-0 in Raleigh, N.C., in 2024.
12:00 PM: Maryland @ Indiana (BTN)
Announcers: Jeff Levering, Jake Butt
The Hoosiers (4-0, 1-0 Big Ten) host the Terrapins (3-1, 0-1). Entering Week 5, Maryland’s Tai Felton ranked second among wide receivers nationwide with 41 grabs and third with 604 yards. Indiana sat fifth in FBS at 50.5 points per game on offense.
12:00 PM: Western Kentucky @ Boston College (ACCN)
Announcers: Jorge Sedano, Orlando Franklin
The Hilltoppers head for the Heights to fly with the Eagles for the first time. Western Kentucky rides a three-game win streak since a season-opening 63-0 loss to Alabama. Boston College also sits 3-1 following a 23-19 victory over Michigan State.
12:00 PM: Holy Cross @ Syracuse (ESPN+, ACCNX)
Announcers: Noah Reed, Craig Haubert
12:00 PM: Buffalo @ Connecticut (CBSSN)
Announcers: Jordan Kent, Logan Ryan, Keiana Martin
The Bulls look to claim another pelt as they visit the Huskies. Buffalo knocked the then-No. 23 Northern Illinois Huskies out of the national rankings with a 23-20 overtime victory in Week 4. The Bulls snapped an eight-game series slide in 2013.
12:00 PM: Nebraska @ Purdue (Peacock)
Announcers: Jac Collinsworth, Michael Robinson
1:30 PM: Ball State @ James Madison (ESPN+)
Announcers: Curt Dudley, Brian Barlow, David Hulvey
3:30 PM: (21) Oklahoma @ Auburn (ABC)
Announcers: Joe Tessitore, Jordan Rodgers
The No. 21 Sooners (3-1, 0-1 SEC) make their maiden voyage to Jordan-Hare Stadium for a tussle with the Tigers (2-2, 0-1). Oklahoma dropped its initial SEC game, 25-15 to then-No. 6 Tennessee in Week 4. Auburn comes off a 24-14 setback to Arkansas.
3:30 PM: Wisconsin @ (13) USC (CBS)
Announcers: Brad Nessler, Gary Danielson
The Badgers link up with the Trojans. Both clubs come off losses to ranked opponents in their last outings. Wisconsin beat USC for the first time in the 2015 Holiday Bowl. USC senior Woody Marks has cracked 100 yards rushing in two straight contests.
3:30 PM: Colorado @ UCF (Fox)
Announcers: Jason Benetti, Brock Huard
The Buffaloes roam into the Sunshine State for a Big 12 meeting with the Knights. Colorado comes off a 38-31 victory over Baylor that featured a Hail Mary touchdown pass by Shedeur Sanders and a game-ending forced fumble by Travis Hunter in overtime.
3:30 PM: Fresno State @ UNLV (FS1)
Announcers: Chris Vosters, Charles Arbuckle
The Rebels run into their Mountain West opener against the Bulldogs. Fresno State has won six straight meetings after a 31-24 decision in California in 2023. UNLV last played Sept. 13, when it beat Kansas 23-20 for its first 3-0 start since 1984.
3:30 PM: Georgia Southern @ Georgia State (ESPNU)
Announcers: Clay Matvick, Steve Addazio
Georgia Southern and Georgia State compete in the first edition of the Georgia Grown Bowl. The Eagles ended a three-game Modern Day Hate slide in 2023. Canadian quarterback Christian Veilleux (GAST) has six touchdown passes in three games.
3:30 PM: Louisiana @ Wake Forest (ACCN)
Announcers: Chris Cotter, Rocky Boiman
The Ragin’ Cajuns try to shake a tough loss when they visit the Demon Deacons. Louisiana Lafayette’s perfect season ended Sept. 21 after going back-and-forth with Tulane in a 41-33 setback. Wake Forest’s Hank Bachmeier has four TD passes in 2024.
3:30 PM: San Diego State @ Central Michigan (CBSSN)
Announcers: Chris Lewis, Taylor McHargue
The Chippewas host the Aztecs. In Week 4, Central Michigan leveled its record at 2-2 by outlasting Ball State 37-34. Chris Parker (CMU) had two TDs, including the game-winner. The Aztecs clobbered the Chippewas 48-11 in the 2019 New Mexico Bowl.
3:30 PM: (15) Louisville @ (16) Notre Dame (Peacock)
Announcers: Paul Burmeister, Jason Garrett
3:30 PM: TCU @ Kansas (ESPN+)
Announcers: Lowell Galindo, Fozzy Whittaker
3:30 PM: Akron @ Ohio (ESPN+)
Announcers: Michael Reghi, Marcus Ray
3:30 PM: Eastern Michigan @ Kent State (ESPN+)
Announcers: Shawn Kenney, Ryan Cavanaugh
3:30 PM: Liberty @ Appalachian State (ESPN+)
Announcers: David Jackson, Avery Hall
3:30 PM: Massachusetts @ Miami (OH) (ESPN+)
Announcers: Doug Sherman, Forrest Conoly
3:30 PM: Western Michigan @ Marshall (ESPN+)
Announcers: North Carolina @ Duke
4:00 PM: North Carolina @ Duke (ESPN2)
Announcers: Mike Monaco, Kirk Morrison
The Blue Devils (4-0) and Tar Heels (3-1) play for the Victory Bell in an ACC opener. North Carolina has won five in a row over Duke after a 47-45 double-overtime thriller in 2023. UNC dropped another shootout in Week 4, 70-50 versus James Madison.
4:00 PM: UTSA @ East Carolina (ESPN+)
Announcers: Richard Cross, Reggie Walker
4:15 PM: Mississippi State @ (1) Texas (SECN)
Announcers: Tom Hart, Cole Cubelic
The No. 1 Longhorns make their first foray into SEC action with this matchup against the Bulldogs. Texas last faced Mississippi State in the Cotton Bowl Classic on New Year’s Day 1999, winning 38-11 for its first victory over the Bulldogs since 1921.
5:00 PM: Old Dominion @ Bowling Green (ESPN+)
Announcers: Jason Ross Jr, Tyoka Jackson
6:00 PM: Louisiana Tech @ Florida International (ESPN+)
Announcers: AJ Ricketts, Zach Leston
6:00 PM: UT-Martin @ Kennesaw State (ESPN+)
Announcers: Nolan Alexander, Stan Lewter, Jade Barkett
6:00 PM: Wagner @ Florida Atlantic (ESPN+)
Announcers: Ryan Urquhart, Patrick Murray
7:00 PM: Stanford @ (17) Clemson (ESPN)
Announcers: Mark Jones, Roddy Jones
The Cardinal make their first trip to Death Valley to face the No. 17 Tigers. Stanford needed a last-second field goal by Emmet Kenney to seal its first ACC victory 26-24 at Syracuse in Week 4. Clemson won its conference opener 59-35 versus NC State.
7:00 PM: (18) Iowa State @ Houston (FS1)
Announcers: Eric Collins, Spencer Tillman
The No. 18 Cyclones blow into Houston to play the Cougars. On Sept. 21, Rocco Becht tossed a pair of touchdown passes for the third straight game to begin 2024 as Iowa State improved to 3-0. The Cyclones have won five straight true road games.
7:00 PM: Charlotte @ Rice (ESPN+)
Announcers: Ted Emrich, Charlie Strong
7:00 PM: Tulsa @ North Texas (ESPN+)
Announcers: James Westling, Leger Douzable
7:00 PM: ULM @ Troy (ESPN+)
Announcers: Will Kollmeyer, Ben Stanfield, Junior Louissaint
7:30 PM: (2) Georgia @ (4) Alabama (ABC)
Announcers: Chris Fowler, Kirk Herbstreit
Perennial powers in the No. 2 Bulldogs (3-0, 1-0 SEC) and No. 4 Crimson Tide (3-0, 0-0) renew their raging rivalry. Alabama has won seven of the last eight meetings with the Georgia triumph coming in the 2021 season national championship game.
7:30 PM: (19) Illinois @ (9) Penn State (NBC)
Announcers: Noah Eagle, Todd Blackledge
The No. 9 Nittany Lions host the No. 19 Fighting Illini for a battle of Big Ten unbeatens. Penn State is averaging 41.3 points per game. Illinois seeks its first 5-0 start since 2011 after prevailing at then-No. 22 Nebraska 31-24 in overtime.
7:30 PM: Middle Tennessee @ Memphis (ESPNU)
Announcers: Courtney Lyle, Rene Ingoglia
The Blue Raiders play the Tigers. Memphis gained 659 yards on offense Sept. 21, but lost its conference opener and for the first time this season, 56-44 in a thriller at Navy. Memphis’ Seth Henigan has thrown a TD pass in all 41 career games played.
7:30 PM: (3) Ohio State @ Michigan State (Peacock)
Announcers: Andrew Siciliano, Colt McCoy
7:45 PM: South Alabama @ (14) LSU (SECN)
Announcers: Dave Neal, Aaron Murray
The No. 14 Tigers prepare to dive back into their SEC slate by facing the Jaguars for the first time. LSU has won three in a row after doubling up on UCLA 34-17 on Sept. 21. Garrett Nussmeier threw for 352 yards and three scores in that victory.
8:00 PM: Cincinnati @ Texas Tech (ESPN2)
Announcers: Brian Custer, Rod Gilmore
The Bearcats visit the Red Raiders. Both Big 12 schools are 3-1, 1-0 with two-game win streaks. Tahj Brooks (TTU) cracked 100 yards rushing in all three games he has played in 2024, while quarterback Behren Morton had 11 TD passes in those contests.
8:00 PM: Florida State @ Southern Methodist (ACCN)
Announcers: Wes Durham, Tom Luginbill
The Seminoles visit the Mustangs. Florida State snapped a surprising three-game skid to begin 2024 by outlasting California 14-9 in Week 4. Brashard Smith scored four times to help SMU capture a wild Iron Skillet matchup with TCU, 66-42 on Sept. 21.
8:00 PM: Air Force @ Wyoming (CBSSN)
Announcers: Rich Waltz, Robert Turbin
The Cowboys (0-4, 0-0) try to get on the board when they host the Falcons (1-2, 0-1) in a Mountain West affair. Air Force’s 8-0 start in 2023 included a 34-27 verdict versus Wyoming. Cade Harris (AFA) has three rushing TDs in three games this year.
8:00 PM: New Mexico @ New Mexico State (ESPN+)
Announcers: Adam Young, Danny Knee
10:00 PM: Washington State @ (25) Boise State (FS1)
Announcers: Dan Hellie, Petros Papadakis
The Cougars (4-0) try to usurp the No. 25 Broncos (2-1) in this Week 5 engagement. Boise State earned 69 points from AP Top 25 voters to crack the national ranking for the first time since 2020. Washington State slotted in next at 67 points.
10:15 PM: Arizona @ (10) Utah (ESPN)
Announcers: Dave Flemming, Brock Osweiler
The Wildcats (2-1) play their first Big 12 game, against a former Pac-12 rival in the No. 10 Utes (4-0). Arizona snapped a six-game series slide with a 42-18 victory last season. Utah won its Big 12 opener, 22-19 at then-No. 14 Oklahoma State.
11:00 PM: (8) Oregon @ UCLA (Fox)
Announcers: Connor Onion, Mark Helfrich
The No. 8 Ducks and Bruins renew their rivalry. Oregon won the final four meetings between the two as Pac-12 members. UCLA lost its Big Ten introduction, and comes off a loss to then-No. 16 LSU. Oregon beat rival Oregon State 49-14 on Sept. 14.